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Skin Advisor
Plant-based. Patented technology.

A new generation of eye care

There are active ingredients that open up entirely new perspectives for cosmetics. PDRN is undoubtedly one of them. Hardly any ingredient currently combines pioneering scientific research and cosmetic innovation as impressively as small DNA fragments with special biological properties. With the new PDRN Eye Cream, Dr. Spiller translates these forward-looking findings into a state-of-the-art active ingredient formulation – precisely tailored to the demanding and delicate eye area.

PDRN. Four letters. New perspectives for the skin.

Originally, research into polydeoxyribonucleotides (PDRN) originated in regenerative medicine. The focus of scientific interest primarily lies on biological processes that are essential for the natural renewal, protective function, and structure of the skin. 
The special feature of PDRN lies in its ability to positively influence cellular mechanisms:

  • Increased cell migration: In laboratory studies with vegan PDRN, an increased mobility of skin cells was observed – an essential factor for natural renewal and repair processes.
  • Strengthening of the skin barrier: A proven, increased formation of the structural protein filaggrin contributes to the stability of the stratum corneum and the preservation of the natural moisture balance.
  • Visible revitalization: Clinical studies confirm that both overall skin radiance and the appearance of the eye area are lastingly improved.

Innovative active ingredient technology

Traditionally, PDRN is predominantly obtained from animal sources such as salmon or trout. With the PDRN Eye Cream, Dr. Spiller is taking a consistently forward-looking, vegan path.
As a symbol of renewal and spring awakening, it forms the natural starting basis for this biotechnological breakthrough. Using a patented manufacturing process, ultra-pure DNA fragments with a particularly small and defined molecular size are isolated. The result is an innovative active ingredient that optimally combines a purely plant-based origin with the findings of modern skin research.

The active ingredient concept: Targeted care with a system

Due to its thin skin structure, low lipid content, and daily stress from facial expressions, the eye area places extreme demands on skincare. The PDRN Eye Cream addresses these challenges through a synergistic composition:

  • Against dark circles & puffiness: A special peptide complex and selected plant active ingredients alleviate visible signs of fatigue, making the look noticeably fresher and more relaxed.
  • Intensive moisture & protection: Skin-related lipids and niacinamide support the natural protective layer, promote suppleness, and effectively counteract moisture loss.
  • Smoothing anti-aging power: Antioxidant and skin-soothing components protect against oxidative stress, soften fine lines, and emphasize natural radiance.
Retinol+ Cream
24-Hour Care
Retinol+ Cream
Retinol+ Cream uses the maximum power of retinol to deliver a comprehensive anti-aging effect. This high-performing formula of active ingredients refines the skin’s structure, smoothes wrinkles and infuses the skin with renewed radiance.
Content: 50 ml
CHF 106.80*

Application: The daily eye care ritua

For optimal results, apply the PDRN Eye Cream morning and evening after facial cleansing and toning. Gently distribute a small amount around the eye area using the ring finger. 
An uncomplicated, highly effective ritual for a wide-awake, refreshed look and a visibly refined skin texture. 
Plant-based. Patented technology. Discover the new generation of eye care.

Our Tip – The 30 Second Eye Boost:


  1. Distribute: Gently apply the cream around the eye using the ring finger.

  2. Work along the under-eye area from the inner to the outer corner with light tapping motions.

  3. Gently work along the area above the eye along the orbital bone from the outside inward.

  4. Finish: Finally, gently smooth along the eyebrow area.

blob of cream

What should you keep in mind when using retinol cream?


There are a few tips for using retinol that we recommend you follow:

  1. Using skincare products containing retinol increases the skin's sensitivity to light. It is therefore essential to apply a sufficiently high sun protection factor (e.g. SUMMER GLOW Sun Sensitive SPF 50).
  2. Cosmetics containing retinol should not be used during pregnancy and breastfeeding.
  3. Those new to retinol should allow their skin to gradually become accustomed to the active ingredient. Depending on sensitivity, the frequency of application should therefore be increased from 3 times a week to once a day in the first month. The goal is to use the active ingredient in your daily skincare routine.

Those who are more experienced with retinol can integrate the products into their daily skincare routine immediately.

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